Surgical Solutions

The ability to stop and control bleeding is critically important to all surgical procedures and to the practice of medicine in general. Based on the self-assembling peptide platform technology, 3-D Matrix has obtained CE mark approval for the surgical haemostatic agent PuraStat®.

PuraStat® has a number of unique features that distinguish it from existing products.

Characteristics and advantages of PuraStat®

  • Transparency of PuraStat® maintains a clear view, increasing accuracy and allows checking the efficacy of the application
  • PuraStat® is suited for use in delicate/hard to reach areas since it is “fluid” and can flow into tiny niches and can e.g. spread well over the irregular surface of the liver
  • As PuraStat® does not disturb the site by becoming hard or sticking to tissue, the surgeon has full flexibility throughout the procedure
  • Second application of PuraStat® is possible and easy

 

 

 

  • Additional clips or sutures maybe placed through PuraStat®
  • Long duration of the procedure makes it difficult to use time-limited products / glues; PuraStat® can be used at the beginning, middle and end of the potential long duration of the procedure
  • It does not change in volume even after application, ensuring control and safety at the site
  • “PuraStat® works also in patients with prolonged prothrombin time”1

 

 

Specifically for laparoscopic procedures

  • PuraStat® fits requirements for a hemostat in laparoscopy: precise work in narrow space, inert, transparent, deliverable through long applicator, non-adhesive or clogging. PuraStat® is suitable for various laparoscopic techniques and procedures.
  • Pressure on intra-abdominal surfaces due to the pneumoperitoneum can inhibit bleeding giving a false sense of security regarding hemostasis. Prior to concluding any procedure, surgical sites need to be observed with reduced pressure to assure appropriate hemostasis2 – the transparency of PuraStat®, and its immediate availability for use without any preparation time, make it suited to this application.
1
Masuhara H, Fujii T, Watanabe Y, Koyama N, Tokuhiro K. Novel infectious agent-free hemostatic material (TDM-621) in cardiovascular surgery. Ann Thorac Cardiovasc Surg. 2012;18(5):444-51. Epub 2012 Sep 14. PMID: 22986759
2

Prevention and management of laparo-endoscopic surgical complications, Chapter 1: Pneumoperitoneum. http://laparoscopy.blogs.com/prevention_management/chapter_01_pneumoperitoneum/

If you are interested in learning more and getting connected to your local representative, please contact us.

3-D Matrix Solutions

Endoscopic Solutions

PuraStat® fits requirements for a hemostat in endoscopy and enables precise work in a narrow space. It is inert, transparent, deliverable through endoscopic applicator, non-adhesive and not clogging.

Laboratory Solutions

PuraMatrix® is the first commercial synthetic extracellular matrix (ECM) scaffold based upon self-assembling peptides, enabling cells to be cultured in carefully controlled microenvironments for life science research, pharmaceutical drug discovery and bioproduction.

Surgical Solutions

The ability to stop and control bleeding is critically important to all surgical procedures and to the practice of medicine in general. Based on the self-assembling peptide platform technology, 3-D Matrix has obtained CE mark approval for the surgical haemostatic agent PuraStat®.

Therapy Innovation

The ability of PuraStat® to be applied through the dedicated nozzle and also through the specially designed catheters is ideal for minimally invasive surgery. Application of PuraStat® through small incisions to internal body tissues facilitates haemostasis, at the affected area while reducing the risks associated with open surgeries.